Archive for the “anti-oxidants” Category

For more than a decade, doctors have known that some compound in grapefruit juice interacts with a small number of drugs to triple the amount of that drug absorbed into the bloodstream. While the compound has remained a mystery, doctors simply tell their patients to avoid grapefruit juice while on the medication.

In a study published in the May issue of the American Journal of Clinical Nutrition, however, Paul Watkins, MD, and his colleagues, finally tracked down furanocoumarins as the active ingredient in grapefruit juice causing this unusual reaction. Watkins, the Dr. Verne S. Caviness distinguished professor of medicine at the University of North Carolina, explained that furanocoumarins block an enzyme called CYP3A4 in the wall of the intestine.

“This enzyme normally chews up certain drugs when they are absorbed,” he says. “When you inhibit the enzyme, however, it doesn’t chew up the drug, which means that more of the drug gets absorbed into the bloodstream.

“Research shows it can boost levels of the drug three times. That’s like taking three pills instead of one. This is an average. Some people would not be boosted as much. Others, however, would be boosted more.”

As startling as this sounds, Watkins points out that of the hundreds of different medications that people are treated with, there are only about 10 with any kind of warning about grapefruit juice in the labeling.

“Fortunately, these drugs are safe enough that boosting absorption for most people will be of no consequence. It appears, however, that a rare patient may have adverse symptoms — for example, muscle tenderness with certain cholesterol medications.

“To my knowledge there have been no confirmed reports of deaths occurring as a result of patients taking their medications with grapefruit juice.”

Classes of drugs that interact with grapefruit juice.
Watkins, who is also director of UNC’s General Clinical Research Center and who led the research team, says that grapefruit juice interacts with four major classes of drugs. One class includes some of the medications used to control anxiety.

Another class comprises a minority of drugs used to lower blood pressure, called calcium channel blockers.

Yet another class are those cholesterol-lowering drugs called statins — particularly Nevacor, Zocor and, to a lesser extent, Lipitor.

Finally, grapefruit juice interacts with immunosuppressants — predominantly Cyclosporine A — which is used mainly to prevent transplanted organs from being rejected.

“Grapefruit juice clearly boosts the absorption of these drugs,” says Watkins, again commenting on the general safety of the drug, so the boosting effect for most individuals is not an issue. The only exception to this blanket cloak of safety might be for individuals taking Cyclosporine A, he adds. “Kidney transplant patients, for example, will be taking this drug.”

Identifying furanocoumarins
It was originally assumed that the ingredients responsible for drug interactions were the flavonoids that give grapefruit juice its bitter taste, Watkins says.

“What we did with our study with the Florida Department of Citrus, however, was to remove the furanocoumarins, leaving in the major flavonoids to see if that got rid of the problem — and it did.

“This is the best evidence, to date, that the active ingredient causing drug interactions is not flavonoids, but these compounds called furanocoumarins that appear to be tasteless and are present in very low amounts in grapefruit juice.”

The story doesn’t end here, because each discovery opens doors to other possibilities, one being that it is now technically possible to market furanocoumarin-free grapefruit juice to patients who would otherwise have to avoid grapefruit.

Much more important, it may be possible to add furanocoumarins to the formulations of certain drugs that tend to be poorly or erratically absorbed to improve their oral delivery.

Watkins explained that if you are a drug company and you develop a drug and only 10 percent of it gets into the body, then you do not have a very good drug, so you usually stop developing it.

“The market for adding furanocoumarins to these pills would be primarily for drugs that had been abandoned in development, or given only by intramuscular injection or intravenously, or promising drugs that might be developed in the future.

“Since furanocoumarins are in grapefruit, it seems reasonable to assume that they are safe, so this should be a safe way to improve oral delivery of drugs.”

Safety: The bottom line
“I personally feel that if you have been taking medicine with grapefruit juice every morning, and the drug is working fine, and your physician is happy, then there is no reason to change.”

According to Watkins, there are many people who enjoy grapefruit juice. And there are others whose economic well being depends upon making it. With the hurricanes the south has experienced over the past couple of years, in particular, the citrus industry is really in tough shape.

“The reality is that a rare patient would get into trouble because of the interaction between a drug and grapefruit juice. This is not a public health issue.”

Comments No Comments »

Apart from saving you money, making your own baby food provides fantastic nutrition for your little one and gives you peace of mind. After all you know exactly what’s gone into your baby’s food, how it was prepared and the quality of ingredients used.

Comments No Comments »

Add to Technorati Favorites

Most people around the world have heard about the medicinal benefits of Chinese herbal remedies. These time tested traditional potions have maintained the one of the worlds largest and indeed greatest cultures for thousands of years. Today, few would dispute the benefits of herbal medicines in the hands of experienced and reputable practitioners.

In the advent of the computer age Chinese traditional medicine has gained a great deal of exposure through the Internet. Now there are a great many companies which sell herbal medicines over the Internet. Herbs, like all other organic substances are susceptible to all sorts of microbial infestations which can greatly compromise the quality of the plant and hence the product which you buy. Herbs infested with moulds, viruses or any of the many types of bacteria can loose most if not all of their beneficial medicinal properties and can even become dangerous to consume.

Herbs which are used in traditional Chinese medicine, like any other other cash crop are grown in fields or collected from the wild, they are then harvested, graded,cut to size,dehydrated, checked by quality control (hopefully), packed, stored in warehouses and finally shipped to the store where you buy them or sent directly to you if you buy via direct marketing routes. As you can see, plants used in traditional medicine go through many handling processes before they become the final product which you but. Every time the plant is handled, something of it’s original integrity and quality is lost. This is inevitable in any industry and each stage presents opportunities for cross contamination if the product is handled improperly. As with any product good manufacturing procedures (GMP) are an absolute necessity. Unfortunately, not all people who market traditional Chinese herbs are reputable manufacturers and great care must be taken in choosing which company to buy from.

Usually, the more high tech the facilities of a factory are, the higher product standards will be. Today, a number of Chinese companies are offering medicinal herbs in freeze dried form The advantages of freeze drying are that the raw materials used have to be of a high standard to ensure a stable end product. Secondly, freeze drying is a great way of preserving as many of the original qualities of the plant as possible. Thirdly, because freeze drying is a very quick process, there is no tome for bacterial or mould spores to form and oxidization is prevented. This means that from a food hygiene standpoint you are safeguarded against such micro organisms forming during usage. Fourthly, Freeze dried products deteriorate at a much slower rate than with other methods that are in use, among other things this means that the anti oxidizing properties of the plant(s) are preserved.

Freeze drying also permits the manufacturer to be very inventive during the manufacturing process. He can make blends that are intended to ensure that you the customer get a guaranteed strength of active ingredient and he can also blend different types of herbs to formulate products to make ready to use infusions for specific medical conditions. In addition, ingredients which make a product more palatable can also be added.

Some of these companies claim to have hundreds of blends in their product range which cover a great many medical requirements. If you intend to use traditional Chinese medicine I would strongly recommend that you investigate the possibilities offered by freeze dried technology.

Comments No Comments »

Food spoilage is really nothing more than a natural deterioration of organic matter. Everything in nature has to be broken down so that it can once again become part of the composition of soil. All of the various natural processes that participate in the spoilage of organic material are ultimately directed toward this aim.

Comments 3 Comments »

Add to Technorati Favorites

They say, never judge a book by it’s cover. The same can be said about wine. I have one criteria that I use to judge a good wine and that is how good is it to drink?  Beverage quality and safety is not a science known only to the big wine producers.

I have bought so many expensive wines only to be completely and utterly disappointed that now I have absolutely no inhibitions about buying wine for one tenth of the price. Some small and quite obscure winerys are making very superior wines for a fraction of the price that you would pay for a Chateau Rothschild, for instance. To  find good cheaper wines I make a habit of going to my favorite wine merchants on days when he is having a wine tasting open day and make a point of tasting a good few of the cheaper wines as well as the more expensice ones. A good merchant, if he knows that you have an open mind, will give you tips about “little gems”  he has found. To be honest, usually it is enough to see the wine against the light to know it’s quality 

Generally speaking, about one third of the wines are not worth a second thought. One third are about the standard that you might expect from a three star restaurant and one third are really worth drinking. On deciding which wines I really like, I buy about two or three crates of assorted wines ranging from cabernet sauvignon to beaujolais.  I try do this about every couple of months.

I never let my dinner guests know that they are drinking bargain basement choices because all wine at my table is decantered. All that they ever know is that they are drinking a wine that is well worth drinking. It also gives me a sense of pride to know that I am helping lesser vineyards to raise their heads and take their true place among the established vineyards as truly good wine making professionals. The condition for this is that they continue to produce wines of a superior standard at competitive prices.

Some say that there is a lot of snobbery around the subject of wine drinking. I tend to agree with that to a degree because people who pay great sums for their wine, often have little or no idea of the wine making process. I have, in the past, tasted really expensive wines to which hydrochloric acid has been added in an attempt to cover up faults in the fermentation process. To those who know about wine, that is one of the most grievous cardinal sins possible to commit. Hydrochloric acid, when diluted to a concentration of five percent is synthetic vinegar. I don’t know about you but I most certainly do not want vinegar in my wine.

Adding hydrochloric acid is a technique that is sometimes used by winemakers who have fouled up the natural acid balance within the wine. By adding hydrochloric acid they are able to cover their mistakes to some degree and hopefully, those who are not experts in wine tasting will never know the difference.

If vineyards are faced with the eventuality of selling the majority of their years production as red wine vinegar they are tempted to use such inferior tactics. So, beware. It’s well worth Joining a good wine tasting course so that you’ll know the difference between good and bad wine and indeed, learn how to enjoy your wine much more.

Part of making really great wine has to do with maintaining correct hygiene conditions. We should always remember that the wine making process uses the yeast which is a naturally occuring micro-organism which grows on the skin of the grape. During the fermentation process the grape juice can pick up many forms of cross contamination in the form of various types of bacteria or undesirable forms of fungus which, if not prevent from entering the grape juice, will spoil or reduce the quality of the final wine. Cross contamination may well be the main cause of wine spoilage. All wineries are susceptible to  contamination precicely for the reason that they are processing a product which comes straight out of a fiels where it has been exposes to the surrounding environment for many months.

So, the message is that there is no absolute connection between the drinkability of wine and price. You will find many, many excellent wines from non label wine makers. Take a little time to discover those you like, enjoy the thrill of discovering priceless gems in the most unexpected places and save yourself a whole lot of money at the same time.

Comments No Comments »

Add to Technorati Favorites

In our modern world there’s no question that we all live longer and healthier lives than our forefathers. In saying that we have to remember that life has, in many ways, greater demands on us and we need to stay super fit to remain competitive. Our environment is constantly churning out poisonous chemicals  that react with Free oxygen in our bodies. These chemicals cause damage which we call free radical damage. Free radicals also play a crucial role in areas of food hygiene both directly and indirectly.

Many types pf anti oxidants are used in the food industry. These anti oxidants play a number of roles. Some are used to counter bad odors in food. These odors can come from a number of different causes. Poultry, especially turkey often has unpleasant odors even though the meat itself is not contaminated.  A lot of this has to do with the way the animal is reared. 

Battery grown turkeys are reared in very crowded conditions. There is a lot of dust in the air and the turkeys droppings accumulate as deep litter  more and more until the turkey is literally walking on a layer of droppings that can reach one foot in thickness. In these conditions the birds feathers are constantly in contact with droppings and as you know the feathers pass through the skin into the  lower lawyers of tissue. In conditions such as these there is absolutely no way that the meat of the turkey will not be affected by the conditions in which the turkey is forced to live.

It is for this reason that the poultry meat industry uses antioxidants to counter the odors of turkey meat.

Other reasons for using anti-oxidants in the food industry include to increase the shelf  life of products by using natural anti-oxidizing substances that will help to prevent chemical reactions within the meat that can cause bacteria to begin to develop.

So antioxidants play a crucial role in the food industry which has very clear implications for food hygiene by preventing the development of undesirable qualities within potentially vulnerable products and by lowering the risk of contamination through the neutralization of free radicals that help harmful bacteria to develop.

At a personal level we can lower the risk of free radical harm by making sure that we have a sufficient intake of natural antioxidants. By providing our bodies with a constant supply of antioxidants we fortify the anti-oxidizing systems already in place within our bodies. This makes the fight against disease easier for our natural defenses. 

In this lens I will talk about and give you ideas on how you can slow down free radical damage, quite considerably By making drinks from fruits, vegetables, and herbs that are all readily available to us in our grocer’s store or which we can grow in our gardens, it we are lucky enough to have access to a plot of land.

Vegetables, Fruits And Herbs For Making Health Drinks.

 Here’s a list of products that you can use to make anti-oxidizing drinks:

Fruits:
Kiwi, Persimmon, Noni, Papaya, Cranberry, hibiscus (a flower), blueberry, blackberry, red currant, elderberry, Black currant, bilberry Carob, acai berries, Strawberry, Apple, Passion fruit, Tamarind, red grapefruit.

Vegetables:
Broccoli, carrots, peas, snow peas, alfalfa sprouts, sunflower sprouts, bamboo sprouts, red cabbage, tomatoes, pumpkin, sweet potato, green cabbage, red peppers, pine nuts, wheat grass, onions, Spring Onions, garlic, beetroot, asparagus, aloe Vera, hops, Fennel.

Herbs and Spices:
Rosemary, Sage, Thyme, Basil, oregano, wild hyssop, coriander, parsley, dill, tarragon, mint, Louisa, melissa, lemon grass, ginger, aniseed, cumin seed, cardamon seed, caraway seed, vanilla pod, Clove.

Note: The dry seeds need to be re hydrated before use. Do this in water that has ice in it in the fridge.

Aloe Vera and carob come in the form of concentrates which can be bought at health food stores or at really good department stores or hypermarkets.

The first recipe that I would like to tell you about is really great for people who suffer from stomach problems and it contains a few things not in the product list above.

I like to prepare this drink on a base of carrot juice because it is gentle on the stomach.

Ingredients:
carrots, ginger, aloe vera, lemon grass, stevia (best from “sunrider”),

Extract juice from carrots and a decent sized piece of ginger. Add about 25ml. of aloe vera concentrate, extract juice from lemon grass, add about 10 drops of stevia per glass. MIX AND DRINK.
For optimal results this recipe should be taken 3-4 times a day. Stevia is a natural sweetener and has the added benefit of speeding up the recovery of stomach lesions.

Fruit Detox Drinks 

*Here’s another of my recipes that’s really tasty.

Ingredients: Persimmon, Kiwi, Papaya, Passion fruit.

This recipe is a tropical delight and it doesn’t matter how much of which to put in. Just use as much as you have or experiment to find your favorite combination.

*Another favorite of mine is mixed berries. This can be a little expensive if the berries are out of season so go by what you can afford.

Red currant, Bilberry, Blackberry, blackberry and Cranberry,

Mix in a blender, Blitz and then pass through juicer or just drink.

*A real favorite is a strange combination to many people but it works really well.

Ingredients:
Carob, Tamarind, Carrot juice And Acai Berry (a Brazilian palm fruit).

The secret here is to use the carob to sweeten the mixture. Just put everything through the Juice extractor and stir well or blend.

*The next recipe involves hibiscus flowers which should be bought dried from your health food store. Put a couple of tablespoons of hibiscus in boiling water and leave to stand until the water is dark red.

To this add red grapefruit, apple juice and elderberry juice or juice of any other berry.

So I’ve given you a few ideas for great detoxifying drinks but really you can mix anything out of the list I gave you in any combination. A general rule of thumb when making your mixes is to mix different colors. The different colors have different antioxidant groups in them. Also, try to make your drinks as pulpy as possible, that way you are also taking advantage of the dietary fiber within the fruit.

 

 

Comments No Comments »